सेनो टिरज़ेपटिड लायोफिलाइज़्ड पाउडर थोक थोक मूल्य

विवरण

Dual Incretin Agonist Peptide for Metabolic & Receptor-Signaling Research

Tirzepatide is a synthetic dual incretin research पेप्टाइड investigated for its activity at both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. Its dual receptor-binding profile has made it an important compound in metabolic, endocrine, and receptor-signaling laboratory research.

SENO supplies high-purity Tirzepatide as a lyophilized sterile powder in a broad range of specifications, from TR5 (5mg × 10 vials) to TR120 (120mg × 10 vials). Each batch is manufactured using automated solid-phase peptide synthesis (SPPS), purified by RP-HPLC, and analytically verified using LC-MS.

Available specifications include:

• TR5 — 5mg × 10 vials
• TR10 — 10mg × 10 vials
• TR15 — 15mg × 10 vials
• TR20 — 20mg × 10 vials
• TR30 — 30mg × 10 vials
• TR40 — 40mg × 10 vials
• TR50 — 50mg × 10 vials
• TR60 — 60mg × 10 vials
• TR100 — 100mg × 10 vials
• TR120 — 120mg × 10 vials

यह पेप्टाइड केवल प्रयोगशाला अनुसंधान अनुप्रयोगों के लिए प्रदान किया जाता है।.

What Is Tirzepatide?

Tirzepatide is a synthetic incretin-mimetic peptide engineered to function as a dual agonist of:

• जीआईपी रिसेप्टर्स
• जीएलपी-1 रिसेप्टर्स

The peptide was designed to investigate how simultaneous incretin receptor activation influences:

• metabolic signaling
• glucose regulation pathways
• receptor-binding dynamics
• endocrine communication
• energy balance mechanisms

Its structure incorporates optimized amino acid substitutions intended to enhance receptor affinity and improve resistance to enzymatic degradation during experimental use.

Compared with single-pathway incretin peptides, Tirzepatide provides researchers with a model for studying integrated hormonal signaling and dual receptor pharmacology.

The compound is supplied as a white lyophilized powder to preserve molecular stability during storage and transportation.

अनुसंधान अनुप्रयोग

Tirzepatide is widely utilized in laboratory investigations involving:

• dual incretin receptor signaling
• GLP-1 pathway research
• GIP receptor modulation studies
• metabolic regulation experiments
• glucose homeostasis research
• endocrine signaling analysis
• receptor-binding kinetics
• ligand-receptor interaction studies
• cAMP signaling investigations
• insulin pathway research models
• peptide pharmacodynamics studies
• पूर्व-नैदानिक चयापचय अनुसंधान

The broad specification range from TR5 to TR120 supports both exploratory laboratory studies and larger-scale research workflows.

आणविक सूत्र

C225H348N48O68C_{225}H_{348}N_{48}O_{68}C225​H348​N48​O68​

आणविक द्रव्यमान

$4813.5g/mol$

सीएएस संख्या

उत्पाद विनिर्देश

क्रिया की क्रियाविधि

Tirzepatide is investigated for its dual agonist activity at both GIP and GLP-1 receptors.

GLP-1 Receptor Pathway

Research involving GLP-1 receptor activation commonly examines:

• glucose-regulatory signaling
• इंसुलिन-संबंधित मार्ग
• receptor internalization mechanisms
• incretin-mediated cellular responses

GIP Receptor Pathway

GIP receptor investigations may include:

• endocrine signaling dynamics
• energy metabolism pathways
• ग्राही औषधशास्त्र
• ligand-binding behavior

The combined receptor activity allows researchers to study how simultaneous incretin pathway modulation influences complex metabolic signaling systems.

घुलनशीलता

Tirzepatide is generally soluble in:

• निर्जीव जल
• जीवाणुरोधी जल
• फॉस्फेट-बफर सलाइन (पीबीएस)
• selected laboratory research buffers

Typical research preparation concentrations may range between:

$0.5-2mg/mL$

Actual solubility and working concentrations depend on:

• experimental design
• preparation conditions
• pH environment
• analytical requirements

Researchers often aliquot prepared solutions to reduce degradation associated with repeated freeze-thaw cycles.

भंडारण अनुशंसाएँ

For optimal stability:

• Store lyophilized peptide at -20°C
• सीधी रोशनी और नमी से बचाएं
• बार-बार तापमान में उतार-चढ़ाव से बचें
• Maintain sterile handling procedures

पुनर्गठन के बाद:

• Store at 2–8°C
• Use within a limited time period
• Minimize freeze-thaw exposure whenever possible

स्थिरता संबंधी जानकारी

Tirzepatide is supplied in lyophilized form to improve structural stability during long-term storage and transportation.

Peptide stability may be influenced by:

• तापमान का प्रभाव
• ऑक्सीकरण
• जल-अपघटन
• जीवाणु संदूषण
• पीएच परिस्थितियाँ
• बार-बार जमने-पगलाने की प्रक्रिया

Controlled lyophilization helps reduce moisture-related degradation and supports peptide integrity during research workflows.

अनुसंधान अध्ययन और वैज्ञानिक रुचि

Tirzepatide has become a major focus in incretin biology and metabolic signaling research due to its dual receptor-targeting design.

Areas of scientific investigation include:

• incretin pathway interactions
• endocrine system signaling
• receptor pharmacodynamics
• glucose metabolism studies
• ligand-binding mechanisms
• cellular signaling pathways
• peptide-receptor interaction models
• integrated metabolic regulation research

Its dual agonist mechanism has expanded research interest in multi-target peptide pharmacology and combined receptor modulation strategies.

निर्माण एवं गुणवत्ता आश्वासन

SENO manufactures Tirzepatide using automated solid-phase peptide synthesis (SPPS) systems under controlled cleanroom laboratory conditions.

उत्पादन कार्यप्रवाह में शामिल हैं:

• high-purity amino acid sourcing
• optimized coupling chemistry
• automated peptide elongation
• preparative RP-HPLC purification
• LC-MS molecular verification
• controlled sterile lyophilization

Each production batch undergoes analytical validation to confirm:

• sequence integrity
• आणविक पहचान
• शुद्धता एकरूपता
• बैच पुनरुत्पादनशीलता

This manufacturing process supports reliable performance in sensitive receptor-signaling and metabolic research studies.

सीओए (विश्लेषण प्रमाणपत्र)

विश्लेषणात्मक दस्तावेज़ीकरण में शामिल हो सकते हैं:

• बैच संख्या
• HPLC purity results
• LC-MS verification
• दृश्य निरीक्षण
• निर्माण तिथि
• storage conditions
• quality-control confirmation

COA documentation supports laboratory traceability and internal research quality assurance.

HPLC & LC-MS Verification

Each batch undergoes analytical assessment using:

• Reverse-Phase HPLC (RP-HPLC)
• Liquid Chromatography-Mass Spectrometry (LC-MS)

These methods help verify:

• पेप्टाइड शुद्धता
• molecular weight
• sequence consistency
• impurity assessment
• batch-to-batch reproducibility

Analytical chromatograms and molecular verification data may be available for laboratory documentation purposes.

पुनर्गठन मार्गदर्शिका

अनुशंसित प्रयोगशाला प्रक्रिया

1. Allow vial to equilibrate to room temperature before opening.
2. Prepare sterile water or suitable research buffer.
3. धीरे-धीरे वायल की दीवार के साथ सॉल्वेंट इंजेक्ट करें।.
4. Avoid direct force onto the lyophilized powder.
5. धीरे-धीरे घुमाएँ जब तक यह पूरी तरह घुल न जाए।.
6. जोर से हिलाएं नहीं।.
7. Aliquot into smaller sterile containers if needed.
8. Store prepared solutions according to experimental requirements.

Researchers should optimize concentrations according to individual laboratory protocols.

सावधानियाँ

• केवल प्रयोगशाला अनुसंधान उपयोग के लिए
• मानव या पशु चिकित्सा के लिए अभिप्रेत नहीं
• Use appropriate PPE during handling
• Maintain aseptic preparation conditions
• बार-बार जमने-पिघलने की प्रक्रिया से बचें।
• Dispose of materials according to institutional safety procedures

शिपिंग जानकारी

• Worldwide FedEx or equivalent express shipping
• Delivered as lyophilized powder for enhanced transport stability
• Ambient temperature shipping with protective packaging
• Designed for international laboratory supply workflows

अक्सर पूछे जाने वाले प्रश्न (FAQ)

What is Tirzepatide used for in research?

Tirzepatide is commonly studied in metabolic, endocrine, incretin signaling, and receptor pharmacology research involving GLP-1 and GIP pathways.

Why is Tirzepatide considered a dual agonist?

The peptide is engineered to activate both GIP and GLP-1 receptors, allowing researchers to investigate integrated incretin signaling mechanisms.

Why is the peptide supplied in lyophilized form?

Lyophilization helps improve peptide stability by reducing moisture exposure during storage and international transport.

What analytical methods are used for quality verification?

Each batch is analytically verified using RP-HPLC and LC-MS to confirm purity, molecular identity, and batch consistency.

How should Tirzepatide be stored?

Lyophilized peptide should generally be stored at -20°C. Reconstituted solutions are typically stored at 2–8°C for short-term laboratory use.

Is this product intended for therapeutic or medical use?

No. Tirzepatide supplied by SENO is strictly intended for laboratory research applications only and is not approved for human or veterinary use.