SENO тирзепатид лиофилизированный порошок оптовая цена

Описание

Dual Incretin Agonist Peptide for Metabolic & Receptor-Signaling Research

Tirzepatide is a synthetic dual incretin research пептид investigated for its activity at both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. Its dual receptor-binding profile has made it an important compound in metabolic, endocrine, and receptor-signaling laboratory research.

SENO supplies high-purity Tirzepatide as a lyophilized sterile powder in a broad range of specifications, from TR5 (5mg × 10 vials) to TR120 (120mg × 10 vials). Each batch is manufactured using automated solid-phase peptide synthesis (SPPS), purified by RP-HPLC, and analytically verified using LC-MS.

Available specifications include:

• TR5 — 5mg × 10 vials
• TR10 — 10mg × 10 vials
• TR15 — 15mg × 10 vials
• TR20 — 20mg × 10 vials
• TR30 — 30mg × 10 vials
• TR40 — 40mg × 10 vials
• TR50 — 50mg × 10 vials
• TR60 — 60mg × 10 vials
• TR100 — 100mg × 10 vials
• TR120 — 120mg × 10 vials

This peptide is supplied exclusively for laboratory research applications.

What Is Tirzepatide?

Tirzepatide is a synthetic incretin-mimetic peptide engineered to function as a dual agonist of:

• GIP receptors
• GLP-1 receptors

The peptide was designed to investigate how simultaneous incretin receptor activation influences:

• metabolic signaling
• glucose regulation pathways
• receptor-binding dynamics
• эндокринная связь
• energy balance mechanisms

Its structure incorporates optimized amino acid substitutions intended to enhance receptor affinity and improve resistance to enzymatic degradation during experimental use.

Compared with single-pathway incretin peptides, Tirzepatide provides researchers with a model for studying integrated hormonal signaling and dual receptor pharmacology.

The compound is supplied as a white lyophilized powder to preserve molecular stability during storage and transportation.

Исследовательские приложения

Tirzepatide is widely utilized in laboratory investigations involving:

• dual incretin receptor signaling
• GLP-1 pathway research
• GIP receptor modulation studies
• metabolic regulation experiments
• glucose homeostasis research
• endocrine signaling analysis
• receptor-binding kinetics
• ligand-receptor interaction studies
• cAMP signaling investigations
• insulin pathway research models
• peptide pharmacodynamics studies
• preclinical metabolic research

The broad specification range from TR5 to TR120 supports both exploratory laboratory studies and larger-scale research workflows.

Молекулярная формула

C225H348N48O68C_{225}H_{348}N_{48}O_{68}C225​H348​N48​O68​

Молекулярная масса

$4813.5g/mol$

Номер CAS

Технические характеристики продукта

Механизм действия

Tirzepatide is investigated for its dual agonist activity at both GIP and GLP-1 receptors.

GLP-1 Receptor Pathway

Research involving GLP-1 receptor activation commonly examines:

• glucose-regulatory signaling
• insulin-related pathways
• receptor internalization mechanisms
• incretin-mediated cellular responses

GIP Receptor Pathway

GIP receptor investigations may include:

• endocrine signaling dynamics
• energy metabolism pathways
• фармакология рецепторов
• ligand-binding behavior

The combined receptor activity allows researchers to study how simultaneous incretin pathway modulation influences complex metabolic signaling systems.

Растворимость

Tirzepatide is generally soluble in:

• стерильная вода
• бактериостатическая вода
• фосфатно-буферный солевой раствор (PBS)
• выбранные буферы для лабораторных исследований

Typical research preparation concentrations may range between:

$0.5-2mg/mL$

Actual solubility and working concentrations depend on:

• experimental design
• preparation conditions
• pH environment
• analytical requirements

Researchers often aliquot prepared solutions to reduce degradation associated with repeated freeze-thaw cycles.

Рекомендации по хранению

For optimal stability:

• Хранить лиофилизированный пептид при температуре -20°C
• Protect from direct light and moisture
• Избегайте резких перепадов температуры
• Maintain sterile handling procedures

После восстановления:

• Store at 2–8°C
• Use within a limited time period
• Minimize freeze-thaw exposure whenever possible

Информация о стабильности

Tirzepatide is supplied in lyophilized form to improve structural stability during long-term storage and transportation.

Peptide stability may be influenced by:

• температурное воздействие
• окисление
• гидролиз
• микробное загрязнение
• pH conditions
• многократные циклы замораживания-размораживания

Controlled lyophilization helps reduce moisture-related degradation and supports peptide integrity during research workflows.

Научные исследования и научный интерес

Tirzepatide has become a major focus in incretin biology and metabolic signaling research due to its dual receptor-targeting design.

Areas of scientific investigation include:

• incretin pathway interactions
• endocrine system signaling
• receptor pharmacodynamics
• glucose metabolism studies
• ligand-binding mechanisms
• клеточные сигнальные пути
• peptide-receptor interaction models
• integrated metabolic regulation research

Its dual agonist mechanism has expanded research interest in multi-target peptide pharmacology and combined receptor modulation strategies.

Производство и обеспечение качества

SENO manufactures Tirzepatide using automated solid-phase peptide synthesis (SPPS) systems under controlled cleanroom laboratory conditions.

Производственный процесс включает в себя:

• high-purity amino acid sourcing
• optimized coupling chemistry
• automated peptide elongation
• preparative RP-HPLC purification
• LC-MS molecular verification
• controlled sterile lyophilization

Each production batch undergoes analytical validation to confirm:

• целостность последовательности
• молекулярная идентичность
• чистота консистенция
• воспроизводимость партии

This manufacturing process supports reliable performance in sensitive receptor-signaling and metabolic research studies.

COA (сертификат анализа)

Аналитическая документация может включать:

• номер партии
• HPLC purity results
• Проверка методом ЖХ-МС
• проверка внешнего вида
• дата изготовления
• storage conditions
• quality-control confirmation

COA documentation supports laboratory traceability and internal research quality assurance.

HPLC & LC-MS Verification

Каждая партия проходит аналитическую оценку с использованием:

• Reverse-Phase HPLC (RP-HPLC)
• Liquid Chromatography-Mass Spectrometry (LC-MS)

Эти методы помогают проверить:

• чистота пептидов
• molecular weight
• sequence consistency
• оценка примесей
• batch-to-batch reproducibility

Analytical chromatograms and molecular verification data may be available for laboratory documentation purposes.

Руководство по восстановлению

Рекомендуемая лабораторная процедура

1. Allow vial to equilibrate to room temperature before opening.
2. Prepare sterile water or suitable research buffer.
3. Slowly inject solvent along the vial wall.
4. Avoid direct force onto the lyophilized powder.
5. Слегка взбейте до полного растворения.
6. Do not shake vigorously.
7. Aliquot into smaller sterile containers if needed.
8. Store prepared solutions according to experimental requirements.

Researchers should optimize concentrations according to individual laboratory protocols.

Меры предосторожности при обращении

• Только для лабораторных исследований
• Не предназначен для применения у людей или в ветеринарии
• Use appropriate PPE during handling
• Maintain aseptic preparation conditions
• Избегайте повторяющихся циклов замораживания-размораживания
• Dispose of materials according to institutional safety procedures

Информация о доставке

• Worldwide FedEx or equivalent express shipping
• Delivered as lyophilized powder for enhanced transport stability
• Доставка при температуре окружающей среды в защитной упаковке
• Designed for international laboratory supply workflows

Часто задаваемые вопросы (FAQ)

What is Tirzepatide used for in research?

Tirzepatide is commonly studied in metabolic, endocrine, incretin signaling, and receptor pharmacology research involving GLP-1 and GIP pathways.

Why is Tirzepatide considered a dual agonist?

The peptide is engineered to activate both GIP and GLP-1 receptors, allowing researchers to investigate integrated incretin signaling mechanisms.

Почему пептид поставляется в лиофилизированной форме?

Lyophilization helps improve peptide stability by reducing moisture exposure during storage and international transport.

Какие аналитические методы используются для проверки качества?

Each batch is analytically verified using RP-HPLC and LC-MS to confirm purity, molecular identity, and batch consistency.

How should Tirzepatide be stored?

Lyophilized peptide should generally be stored at -20°C. Reconstituted solutions are typically stored at 2–8°C for short-term laboratory use.

Предназначен ли этот продукт для терапевтического или медицинского использования?

No. Tirzepatide supplied by SENO is strictly intended for laboratory research applications only and is not approved for human or veterinary use.